张浩林

      张浩林，副教授，2017年5月加入ManBetX中国官网生物科学与

技术学院动物学科，现承担《免疫学》、《动物生理学A》、《

动物学实验》等课程。主要研究方向为动物生理学，关注野生动

物、林下经济动物特殊生理现象的内分泌调控机制及相关产业化

应用，先后主持国家自然基金青年项目与面上项目、北京市自然

基金面上项目、科技部外国专家项目等。目前共发表SCI论文70

余篇，其中以第一作者或通讯作者在Integrative Zoology、

Environmental Pollution、Chemico-Biological Interactions、

Nanoscales、FASEB Journal、Journal of Steroids Biochemistry and

Molecular Biology、Cells、American Journal of Physiology- Regulatory, Integrative and Comparative Physiology、Biology of Reproduction等重要国际期刊上发表20余篇论文。担任Metabolites杂志特邀编辑。曾获得ManBetX中国官网优秀教案一等奖、ManBetX中国官网教学成果奖一等奖（排名第二）、ManBetX中国官网第十八届青年教师教学基本功比赛特色组一等奖，首批国家级线下一流本科课程《动物生理学A》共同承担人，指导学生开展大学生创新创业训练计划，带领学生团队在中国“互联网+”大学生创新创业大赛、全国大学生生命科学竞赛、“挑战杯”课外学术科技作品竞赛等比赛中取得优异成绩。

Email：haolinzhang@bjfu.edu.cn

研究方向：

动物生殖生物学

野生动物与林下经济动物特殊生理调控机制

动物进化与发育生物学

主持或参与基金项目：

国家自然基金面上项目，基于达乌尔黄鼠动物模型研究上皮细胞可塑性与异质性在前列腺季节性增生与回缩中的作用，主持

国家自然基金青年科学基金项目，机动车尾气中4-硝基苯酚干扰节律基因表达影响大鼠卵巢功能机理研究，主持

北京市自然基金面上项目，麝鼠泌香腺内麝香酮生物合成途径研究，主持

北京市自然基金面上项目，北京机动车尾气中 3-甲基-4-硝基苯酚暴露干扰节律系统影响雌性生殖功能的跨代效应，参与

国家自然基金面上项目，雄激素调控麝鼠香囊腺分泌麝鼠香的分子机制研究，参与

北京市自然基金面上项目，北京市机动车尾气中3-甲基-4硝基苯酚干扰大鼠卵巢功能分子机理研究，参与

ManBetX中国官网新进教师基金，性类固醇激素对麝鼠香囊腺泌香功能调控作用研究，主持

近年来发表论文：

1. Xie W, Gao Q, Chen P, Zhang H, Liu Y, Weng Q. Seasonal expressions of the translocator protein (18 kDa), voltage-dependent anion channel, and steroidogenic acute regulatory protein in the scent glands of muskrats (Ondatra zibethicus). Journal of Steroid Biochemistry and Molecular Biology. 2023;234:106400.

2. Xie W, Chen M, Shen Y, Liu Y, Zhang H, Weng Q. Vomeronasal Receptors Associated with Circulating Estrogen Processing Chemosensory Cues in Semi-Aquatic Mammals. International journal of molecular sciences. 2023;24(13):10724.

3. Xie W, Zhang C, Gao Q, Liu Y, Zhang H, Weng Q. Seasonal expressions of COX-1, COX-2, and EP4 in the scent glands of muskrats (Ondatra zibethicus). American journal of physiology. Regulatory, integrative and comparative physiology. 2023;325(3):R238-R247.

4. Yu W, Fan S, Wang X, Zhu J, Yuan Z, Han Y, et al. Seasonal change of circulating leptin associated with testicular activities of the wild ground squirrels (Citellus dauricus). Integrative zoology. 2023;18(1):76-92.

5. Song F, Xu Y, Peng P, Li H, Zheng R, Zhang H, et al. Seasonal Changes in the Structure and Function of Gut Microbiota in the Muskrat (Ondatra zibethicus). Metabolites. 2023;13(2):699797.

6. Zhang H, Chen P, Liu Y, Xie W, Fan S, Yao Y, et al. Estrogen signaling regulates seasonal changes of the prostate in wild ground squirrels (Spermophilus dauricus). The Journal of steroid biochemistry and molecular biology. 2022;218:106058.

7. Yang X, Liu X, Song F, Wei H, Gao F, Zhang H, et al. Seasonal expressions of GPR41 and GPR43 in the colon of the wild ground squirrels (Spermophilus dauricus). European journal of histochemistry. 2022;66(1): 3351.

8. Xie W, Mu S, Zhong J, Zhang C, Zhang H, Wang X, et al. Mass Spectrometry Imaging of Lipids in the Scent Glands of Muskrat (Ondatra zibethicus) in Different Reproductive Statuses. Cells. 2022;11(14): 2228.

9. Tang Z, Yuan X, Bai Y, Guo Y, Zhang H, Han Y, et al. Seasonal changes in the expression of PACAP, VPAC1, VPAC2, PAC1 and testicular activity in the testis of the muskrat (Ondatra zibethicus). European journal of histochemistry. 2022;66(2): 3398.

10. Song Y, Yang X, Zhang X, Zhu J, Chen Y, Gao F, et al. Seasonal expression of extracellular signal regulated kinases in the colon of wild ground squirrels (Spermophilus dauricus). Molecular biology reports. 2022;49(3):2209-15.

11. Fan S, Zhao X, Xie W, Yang X, Yu W, Tang Z, et al. The effect of 3-Methyl-4-Nitrophenol on the early ovarian follicle development in mice by disrupting the clock genes expression. Chemico-biological interactions. 2022;363:110001.

12. Fan S, Lu W, Zhang H, Yuan Z, Han Y, Weng Q. Seasonal Change in Adiponectin Associated with Ovarian Morphology and Function in Wild Ground Squirrels (Citellus dauricus Brandt). International journal of molecular sciences. 2022;23(23): 14698.

13. Fan C, Liu Y, Wang Y, Zhang A, Xie W, Zhang H, et al. Expression of glycogenic genes in the oviduct of Chinese brown frog (Rana dybowskii) during pre-brumation. Theriogenology. 2022;185:78-87.

14. Zhang H, Liu H, Kataoka S, Kinukawa M, Uchiyama K, Kambe J, et al. L-amino acid oxidase 1 in sperm is associated with reproductive performance in male mice and bulls. Biology of Reproduction. 2021;104(5):1154-61.

15. Yao Y, Xie W, Chen D, Han Y, Yuan Z, Zhang H, et al. Seasonal expressions of VEGF and its receptors VEGFR1 and VEGFR2 in the prostate of the wild ground squirrels (Spermophilus dauricus). European journal of histochemistry. 2021;65(2): 3219.

16. Yang X, Yao Y, Zhang X, Zhong J, Gao F, Zhang H, et al. Seasonal Changes in the Distinct Taxonomy and Function of the Gut Microbiota in the Wild Ground Squirrel (Spermophilus dauricus). Animals. 2021;11(9):2685.

17. Xie W, Zhao X, Guo L, Han Y, Yuan Z, Zhang H, et al. Seasonal expressions of ER alpha, ER beta, EGF, EGFR, PI3K and Akt in the scent glands of the muskrats (Ondatra zibethicus). Journal of Steroid Biochemistry and Molecular Biology. 2021;213:105961.

18. Wang Y, Su R, Liu P, Yuan Z, Han Y, Zhang H, et al. Seasonal changes of mitochondrial autophagy and oxidative response in the testis of the wild ground squirrels (Spermophilus dauricus). American Journal of Physiology-Regulatory Integrative and Comparative Physiology. 2021;321(4):R625-R33.

19. Wang Y, Qi H, Zhang C, Guo Y, Yao Y, Feng X, et al. The seasonal profile of proliferation and apoptosis in the prostate gland of the wild ground squirrel (Spermophilus dauricus). Comparative Biochemistry and Physiology a-Molecular & Integrative Physiology. 2021;253:110862.

20. Tang Z, Chen Y, Ren B, Wang X, Zhang H, Han Y, et al. Immunoreactivities of AR, ER alpha, ER beta and aromatase in the nuptial pad of Chinese brown frog (Rana dybowskii) during pre-hibernation and the breeding period. European Journal of Histochemistry. 2021;65(2):3206.

21. Cui F, Pan Q, Wang S, Zhao F, Wang R, Zhang T, et al. Maternal Benzophenone Exposure Impairs Hippocampus Development and Cognitive Function in Mouse Offspring. Adv Sci (Weinh). 2021:e2102686.

22. Yuan Z, Wang Y, Yu W, Xie W, Zhang Z, Wang J, et al. Seasonal expressions of oxytocin and oxytocin receptor in the epididymides in the wild ground squirrels (Citellus Dauricus Brandt). General and Comparative Endocrinology. 2020;289:113391.

23. Yu W, Zhang Z, Liu P, Yang X, Zhang H, Yuan Z, et al. Seasonal expressions of SPAG11A and androgen receptor in the epididymis of the wild ground squirrels (Spermophilus dauricus Brandt). European Journal of Histochemistry. 2020;64(2):120-8.

24. Xie W, Tang Z, Xu L, Zhong J, Zhang H, Han Y, et al. Seasonal expressions of SF-1, StAR and P450scc in the scent glands of the muskrats (Ondatra zibethicus). The Journal of steroid biochemistry and molecular biology. 2020;204:105766.