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李晔

[发布日期:2022-02-21 点击数: ]
 

  李晔,1987年生,河北石家庄人。博士,副教授,硕士生导师,博士生导师。 林木分子设计育种北京市高精尖创新中心青年研究员。

E-mail:liye0223@bjfu.edu.cn
通讯地址:ManBetX中国官网高精尖楼305 
 
 
 
  研究方向  
 

  细胞生物学,纳米-植物相互作用,细胞壁

  近年来,依托主持的国家自然科学基金等项目的支持,基于国际学术前沿,结合材料学、细胞生物学、分子模拟技术等多学科交叉手段,主要开展纳米材料作为药物/基因载体在植物中的跨细胞转运的机理研究。目前本人以第一或通讯作者在《Biomaterials》、《ScienceBulletin》、《Nanoscale》、《Soft Matter》、《Nanoimpact》、《Nanotechnology》等SCI学术期刊发表研究性论文10余篇,多篇论文选入期刊的封面文章,参编著作1部。

 
  学习、工作经历  
 

  2022/01-至今:ManBetX中国官网ManBetX China·中国ManBetX™,细胞生物学学科,副教授、博士生导师

  2021/01-至今:ManBetX中国官网ManBetX China·中国ManBetX™,细胞生物学学科,副教授、硕士生导师、北林学者青年拔尖人才

  2019/12-至今:林木分子设计育种北京市高精尖创新中心青年研究员

  2015/07-2020/12:ManBetX中国官网ManBetX China·中国ManBetX™,细胞生物学学科,讲师

  2010/08-2015/06:北京化工大学,博士(硕博连读)

 
  承担项目  
 

  1. 国家自然科学基金青年科学基金项目拟南芥中网格蛋白介导的选择性胞吞的调控机制” (2017/01-2019/12),  主持

  2. ManBetX中国官网科技创新计划项目壳聚糖复合单壁碳纳米管作为林木基因载体的应用及跨细胞转运的分子机制研究” (2021/06-2022/12),  主持

  3. ManBetX中国官网科技创新计划项目网格蛋白介导的内吞机理的研究” (2015/10-2017/10 ), 主持

 
  成果与奖励  
 

  1. 2022年:教学改革与研究论文三等奖

  2. 2022年:教学改革与研究论文优秀奖

  3. 2020: ManBetX中国官网本科课程优秀教案二等奖

  4. 2020年:ManBetX中国官网教育教学研究论文优秀奖

  5. 2019年:ManBetX中国官网教学基本功比赛实践类 校级三等奖

  6. 2017年:第六届ManBetX中国官网优秀青年学术论文奖二等奖

  7. 2014年:博士研究生国家奖学金

  8. 2012年:硕士研究生国家奖学金

 
  发表文章情况  
 
  • YeLi李晔*,Man Zhang, Xinhui Niu, Tongtao Yue*. Selective membrane wrapping on differently sized nanoparticles regulated by clathrin assembly: A computational model 2022, Colloids and Surfaces B: Biointerfaces, 2022,214:112467. (SCI, IF = 5.268
  • Ye Li 李晔*,Xinhui Niu, Lingzhi Li, Xianren Zhang, Kai Yang* Tongtao Yue*. Size, geometry and mobility of protein assemblage regulate the kinetics of membrane wrapping on nanoparticles. Journal of Molecular Liquids, 2021, 333115990. (SCI,IF = 5.065)
  • Ye Li 李晔*, Zengshuai Yan, Jianwei Xiao, Tongtao Yue*. DNA-conjugated layered double hydroxides penetrating into a plasma membrane: Layer size, thickness and DNA grafting density matter. Nanoimpact, 2020, 100222. (SCI, IF = 5.316 )
  • Ye Li 李晔, Xianren Zhang, Jinxin Lin, Ruili Li*, Tongtao Yue *. Extracting lipid vesicles from plasma membranes via self-assembly of clathrin-inspired scaffolding nanoparticles. Colloids and Surfaces B: Biointerfaces, 2019, 176:39-248. (SCI, IF = 5.268)
  • Ye Li 李晔#*, Wenlong Bao#, Hongyang Wu, Junya Wang, Yu Zhang, Yinglang Wan, Dapeng Cao, Dermot O’Hare, Qiang Wang*. Delaminated layered double hydroxide delivers DNA molecules as sandwich nanostructure into cells via a non-endocytic pathway. Science Bulletin, 2017, 62: 686-692. (SCI, IF = 11.78)
  • Ye Li 李晔, Bing Yuan, Kai Yang*, Xianren Zhang, Bing Yan, Dapeng Cao*. Counterintuitive cooperative endocytosis of like-charged nanoparticles in cellular internalization: computer simulation and experiment. Nanotechnology, 2017, 28. ( SCI, IF = 3.440)
  • Ye Li 李晔, Diwen Feng, Xianren Zhang*, Dapeng Cao*. Design strategy of cell-penetrating copolymers for high efficient drug delivery. Biomaterials, 2015, 52:171-179. (SCI Top, IF = 12.479)
  • Ye Li 李晔, Xianren Zhang*, Dapeng Cao*. Tailoring nanoparticle hardness to control endocytosis for drug delivery. Nanoscale, 2015, 7: 2758 - 2769 (SCI Top, IF= 6.973)
  • Ye Li 李晔, Xianren Zhang*, Dapeng Cao*. Spontaneous penetration mechanism of patterned nanoparticles across a biomembrane. Soft Matter, 2014, 10: 6844-6856. (SCI Top, IF=4.151)
  • Ye Li 李晔, Xianren Zhang*, Dapeng Cao*. The role of shape complementarity in the protein-protein interaction. Scientific Report, 2013, 3: 3271. (SCI, IF=5.078)
  • Ye Li 李晔, Xianren Zhang*, Dapeng Cao*. Self-assembly of patterned nanoparticle on cellular membrnaes: effect of charge distribution. The Journal of Physical Chemistry B, 2013, 117: 6733-6740.(SCI, IF= 3.607)
  • Ye Li 李晔, Tongtao Yue, Kai Yang*, Xianren Zhang*. Molecular modeling of the relationship between nanoparticle shape anisotropy and endocytosis kinetics. Biomaterials, 2012, 33:4965-4973. (SCI Top, IF = 12.479)
  • Edwin H. Shin, Ye Li 李晔, Umesh Kumar, Hursh V. Sureka, Xianren Zhang, Christine K. Payne*. Membrane potential mediates the cellular binding of nanoparticles. Nanoscale, 2013, 5, 5879.(SCI Top, IF= 6.973)
  • Gaoxing Su, Xiaofei Zhou, Hongyu Zhou, Ye Li 李晔, Xianren Zhang, Yin Liu, Dapeng Cao*, Bing Yan*, Size-dependent facilitation of cancer cell targeting by proteins adsorbed on nanoparticles.ACS Applied Materials & Interfaces, 2016, 8: 30037-30047. (SCI Top, IF = 7.504)
  • FaLin Tian, Tongtao Yue, Ye Li 李晔, Xianren Zhang*. Computer simulation studies on the interactions between nanoparticles and cell membrane. Science China Chemistry, 2014, 57: 1662-1671. (SCI, IF = 6.356

  书籍及章节:

  • Falin Tian,  Tongtao Yue, Ye Li 李晔, Xianren Zhang. Simulations on cell uptake of nanoparticles: membrane-mediated interaction, internalization pathways, and cooperative effect, chapter 8 in Self-assembling systems: theory and simulation. John Wiley & Sons: Oxford, UK.2016.
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